TABLE 5.

Comparison of occurrence of vancomycin-induced AKI in different groups of patients based on trough concentration and AUC values using Chi-square test (N = 53).

Pharmacokinetic parameter	Groups	Frequencies (%)	p-value
Trough concentration 1 (µg/ml)	<10	37.70	<0.001
	10–15	28.30
	15–20	15.10
	≥20	18.90
Trough concentration 2 (µg/ml)	<10	41.50	<0.001
	10–15	26.40
	15–20	15.10
	≥20	17.00
AUCτ (µg.h/ml)	<200	52.20	0.001
	200–300	26.10
	≥300	21.70
AUC24h (µg.h/ml)	<400	52.20	0.001
	400–600	26.10
	≥600	21.70