Table 6.
No. | Title | Document type | Journals | First author | Year | LCS | GCS |
---|---|---|---|---|---|---|---|
1 | Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment | Animal study | Science | Iida, N. | 2013 | 70 | 1116 |
2 | Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy | Animal study | Science | Sivan, A. | 2015 | 155 | 1730 |
3 | Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota | Animal study | Science | Vetizou, M. | 2015 | 148 | 1596 |
4 | Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects | Animal and clinical study |
Immunity | Daillere, R. | 2016 | 30 | 347 |
5 | Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis | Clinical study | Nat. Commun. | Dubin, K. | 2016 | 39 | 496 |
6 | Metagenomic Shotgun Sequencing and Unbiased Metabolomic Profiling Identify Specific Human Gut Microbiota and Metabolites Associated with Immune Checkpoint Therapy Efficacy in Melanoma Patients | Clinical study | Neoplasia | Frankel, AE. | 2017 | 40 | 261 |
7 | Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab | Clinical study | Ann. Oncol. | Chaput, N. | 2017 | 64 | 514 |
8 | Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors | Animal and clinical study |
Science | Routy, B. | 2018 | 184 | 2104 |
9 | Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients | Animal and clinical study |
Science | Gopalakrishnan, V. | 2018 | 172 | 1816 |
10 | The gut microbiota influences anticancer immunosurveillance and general health | Review | Nat. Rev. Clin. Oncol. | Routy, B. | 2018 | 25 | 211 |
11 | The Influence of the Gut Microbiome on Cancer, Immunity, and Cancer Immunotherapy | Review | Cancer Cell | Gopalakrishnan, V. | 2018 | 33 | 459 |
12 | Negative association of antibiotics on clinical activity of immune checkpoint inhibitors in patients with advanced renal cell and non-small-cell lung cancer | Clinical study | Ann. Oncol. | Derosa, L. | 2018 | 58 | 376 |
13 | Use of broad-spectrum antibiotics impacts outcome in patients treated with immune checkpoint inhibitors | Clinical study | Oncoimmunology | Ahmed, J. | 2018 | 17 | 72 |
14 | Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis | Clinical study | Nat. Med. | Wang, YH. | 2018 | 18 | 276 |
15 | A defined commensal consortium elicits CD8 T cells and anti-cancer immunity | Animal study | Nature | Tanoue, T. | 2019 | 44 | 396 |
16 | Gut microbiome affects the response to anti-PD-1 immunotherapy in patients with hepatocellular carcinoma | Clinical study | J. Immunother. Cancer | Zheng, Y. | 2019 | 13 | 129 |
17 | The Diversity of Gut Microbiome is Associated With Favorable Responses to Anti-Programmed Death 1 Immunotherapy in Chinese Patients With NSCLC | Clinical study | J. Thorac. Oncol. | Jin, YP. | 2019 | 25 | 144 |
18 | Antibiotics are associated with attenuated efficacy of anti-PD-1/PD-L1 therapies in Chinese patients with advanced non-small cell lung cancer | Clinical study | Lung Cancer | Zhao, S. | 2019 | 17 | 73 |
19 | Antibiotics are associated with decreased progression-free survival of advanced melanoma patients treated with immune checkpoint inhibitors | Clinical study | Oncoimmunology | Elkrief, A. | 2019 | 17 | 91 |
20 | Impact of prior antibiotic use on the efficacy of nivolumab for non-small cell lung cancer | Clinical study | Oncol. Lett. | Hakozaki, T. | 2019 | 15 | 60 |
21 | Association of Prior Antibiotic Treatment With Survival and Response to Immune Checkpoint Inhibitor Therapy in Patients With Cancer | Clinical study | Jama Oncol. | Pinato, DJ. | 2019 | 31 | 189 |
22 | Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy | Animal study | Science | Mager, LF. | 2020 | 13 | 212 |
23 | Cumulative Antibiotic Use Significantly Decreases Efficacy of Checkpoint Inhibitors in Patients with Advanced Cancer | Clinical study | Oncologist | Tinsley, N. | 2020 | 14 | 65 |
24 | Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients | Clinical study | Science | Baruch, EN. | 2021 | 15 | 226 |
25 | Fecal microbiota transplant overcomes resistance to anti-PD-1 therapy in melanoma patients | Clinical study | Science | Davar, D. | 2021 | 15 | 190 |