Table 1.

5-ASA preparations

Preparation	Drug	Formulation	Release site
Azo-bonded prodrugs	Sulfasalazine (Salazopyrin)	Sulfapyridine+5-ASA	Colon
	Olsalazine (Dipentum)	5-ASA+5-ASA	Colon
	Basalazide (Colazal)	4-amino-benzoyl-β-alanine+5-ASA	Colon
pH-dependent drugs	Mesalamine (Asacol)	5-ASA coated with Eudragit S100	Terminal ileum and colon
	Mesalamine (Salofalk)	5-ASA coated with Eudragit L100	Distal ileum and colon
	Mesalamine (Mezavant)	MMX system coated combination with Eudragit S100 and Eudragit L100	Terminal ileum and colon
Time-dependent drugs	Mesalamine (Pentasa)	5-ASA coated with a semipermeable membrane of ethycellulose	Duodenum, small bowel, and colon

5-ASA, 5-aminosalicylate.