TABLE 2.
Baseline characteristics of the IgAN patients.
| Characteristics | IgAN (n = 20) |
|---|---|
| Mean ± SD or n (%) or n | |
| Demographoc | |
| Age (years) | 38.5 ± 8.7 |
| Male gender (%) | 10(50%) |
| Height (m) | 1.6 ± 0.1 |
| Weight (kg) | 57.9 ± 9.9 |
| BMI (kg/m2) | 22.3 ± 3.7 |
| SBP (mmHg) | 125.9 ± 19.4 |
| DBP (mmHg) | 79.6 ± 11.9 |
| MAP (mmHg) | 95.0 ± 13.7 |
| Smoker (%) | 0 |
| Alcohol user (%) | 8 (38.10%) |
| Comorbidities | |
| Hypertension | 5(25%) |
| Hyperlipemia | 6(30%) |
| Diabetes | 0 |
| Hyperuricemia | 6(30%) |
| Chronic Gastritis | 1(5%) |
| Hepatic steatosis | 4(20%) |
| Laboratory values | |
| Hb (g/L) | 131.3 ± 10.7 |
| TP (g/L) | 63.9 ± 8.0 |
| ALB (g/L) | 38.2 ± 6.5 |
| GLB (g/L) | 25.8 ± 3.2 |
| FBG (mmol/L) | 5.8 ± 2.2 |
| sCr (μmol/L) | 97.0 ± 39.2 |
| Urea (mmol/L) | 5.5 ± 1.5 |
| UA (μmol/L) | 420.0 ± 76.5 |
| eGFR (ml/min/1.73㎡) | 84.0 ± 30.0 |
| TG (mmol/L) | 1.8 ± 1.5 |
| TC (mmol/L) | 5.4 ± 1.8 |
| HDL-C (mmol/L) | 1.2 ± 0.4 |
| LDL-C (mmol/L) | 3.7 ± 1.6 |
| hsCRP (mg/L) | 1.9 ± 2.4 |
| IgA (g/L) | 3.2 ± 1.0 |
| IgG (g/L) | 10.2 ± 2.3 |
| IgM (g/L) | 1.1 ± 0.6 |
| C3 (g/L) | 1.1 ± 0.2 |
| C4 (g/L) | 0.2 ± 0.1 |
| CH50 (g/L) | 30.2 ± 7.9 |
| U-RBC (cells/μL) | 95.4 ± 142.5 |
| 24h U-PRO (g/24h) | 1.7 ± 2.7 |
| uPCR (g/g) | 1.9 ± 4.4 |
| D-RBC/U-RBC | 0.8 ± 0.2 |
| kapU (mg/L) | 71.0 ± 142.7 |
| lamU (mg/L) | 44.4 ± 99.4 |
| IgGU (mg/L) | 85.1 ± 86.3 |
| β2-Mg (mg/L) | 0.9 ± 1.8 |
| ALBU (mg/L) | 2226.1 ± 4784.1 |
| α1-MU (mg/L) | 26.2 ± 38.0 |
| α2-MU (mg/L) | 4.6 ± 5.2 |
| TrfU (mg/L) | 53.6 ± 42.1 |
| Histological findings, n | |
| M0/M1 | 1/19 |
| E0/E1 | 17/3 |
| S0/1S | 14/6 |
| T0/T1/T2 | 16/3/1 |
| C0/C1/C2 | 6/13/1 |
BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure; Hb, hemoglobin; TP, total protein; ALB, albumin; GLB, globulin; FBG, fasting blood glucose; sCr, serum creatinine; UA, uric acid; eGFR, estimated glomerular filtration rate; TG, triglyceride; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; hsCRP, high-sensitivity C-reactive protein; IgA, immunoglobulin A; IgG, immunoglobulin G; IgM, immunoglobulin M; C3, complement three; C4, complement 4; CH50, total complement activity; U-RBC, urine red blood cells; 24 h U-PRO, 24-hour urine protein; uPCR, urine protein creatinine ratio; kapU, urine immunoglobulin kap; lamU, urine immunoglobulin lam; IgGU, urine immunoglobulin G; β2-Mg, urine β2-microglobulin; ALBU, albuminuria; α1-MU, urine α1 microglobulin; α2-MU, urine α2 macroglobulin; TrfU, urine Transferrin; M, mesangial hypercellularity; E, endocapillary hypercellularity; S, segmental sclerosis; T, tubular atrophy/interstitial fibrosis; C crescents.