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. 2022 Aug 24;13:970280. doi: 10.3389/fphar.2022.970280

TABLE 2.

Confirmed Oncosuppressor miRNAs in Prostate Cancer a .

Stilbene miRNA Identified Target Associated information or Events References
No treatment miR-654-5p AR PSA, LNCaP cell proliferation Ostling et al. (2011)
No treatment miR-149 AR CRCP 22-Rv1 cells Zhao et al. (2021)
P13K/Akt1
No treatment miR-149-5p RGS17 Viability, proliferation, migration of 22Rv1 and C4-2 cells , high in prostate cancer tissues Ma et al. (2021)
No treatment miR-1231 EGFR Cell proliferation, migration, invasion in DU145, 22Rv1, PC3, and VCaP, high in prostate cancer tissues Wang Y et al. (2020)
No treatment miR-939-3p BCYRN1/HDAC11 Cell proliferation, Huo et al. (2020)
Decreased in prostate cancer tissues vs. normal
No treatment miR-1908 SRM 22Rv1 cells, high in prostate cancer tissues Urabe et al. (2020)
No treatment miR-1915-3p Upregulation was linked to recurrence-free survival Ali et al. (2021)
Independent prognostic marker
a

These miRNAs are putative stilbene-regulated oncosuppressor miRs previously identified by Dhar et al., 2011.