Table 1.
The clinical characteristic of the studied groups in context of laboratory parameters - type 1 diabetic pediatric patients (T1D) and healthy control (HC).
| Parameter | Type 1 Diabetesmellitus (T1D) Onset | Type 1 Diabetesmellitus (T1D) After 2 years | Control Group (HC) |
|---|---|---|---|
| Age [years] |
11.0 (9.0; 13.5) |
13.5 (9.5; 14.5) |
|
| Body Mass Index [kg/m2] |
15.80 (14.70; 18.40) |
19.30####
(17.0; 22.60) |
20.30**
(16.0; 22.20) |
| SDS-BMI | -0.500 (-1.11;0.39) |
0.463####(-0.454;1.273) | 0.460**
(-0.410;1.150) |
| Glucose level [mg/dl] |
428.5 (296.8; 521.8) |
86.0***
(80.50; 90.50) |
|
| HbA1c [%] |
11.46 (10.46; 14.19) |
6.86####
(6.248; 7.535) |
|
| C-peptide [μ/L] |
0.54 (0.34; 0.81) |
0.44 (0.155; 0.785) |
|
| GADA [IU/ml] |
71.43 (6.55; 289.2) |
||
| IA2A [IU/ml] |
437.2 (5.35; 1184) |
||
| ICA [IU/ml] |
20 (0; 40) |
Data was presented as a median value with 25th and 75th interquartile range in the brackets. (*- difference between T1D in onset time and HC, # - difference between T1D in onset time and after 2years treatment). The levels of significant differences were indicated with asterisks or exact p values: ** p < 0.01; ***p < 0.001; and octothorpe ####p < 0.0001 respectively.