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. 2022 Aug 24;13:910993. doi: 10.3389/fimmu.2022.910993

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Copyright © 2022 Soliman, Stanley, Vanarsa, Ismail, Mok and Mohan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation of Serum and Urine protein biomarkers in SLE patients and controls. For each subject, the corresponding values of the protein in urine and serum were considered, in order to ascertain any correlation between these 2 measures. Intensity of blue color represents the strength of serum/urine correlations in each of the 4 subject groups examined, while the size of the circles represents urine biomarker level in each group compared to the level in the active LN group; in all cases the biomarker level in active LN was set to be 100%, corresponding to the maximal circle size.