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. 2022 Aug 24;9:972569. doi: 10.3389/fnut.2022.972569

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Copyright © 2022 Zhou, Qureshi, Xue, Xie, Li and Gu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Grouping of C57BL/6 mice for prevention and therapeutic models. (A) The preventive groups of control (normal mice without prevention and infection in the preventive group), Hp (mice infected with H. pylori without prevention in the preventive group), 54 (only treated with L. paracasei ZFM54), and 54+Hp (pretreatment with L. paracasei ZFM54 before H. pylori challenge). (B) The therapeutic groups of control' (normal mice without prevention and infection in the therapeutic group), Hp' (mice infected with H. pylori without treatment in the therapeutic group), Hp+54 (treatment with L. paracasei ZFM54 after H. pylori challenge), and Hp+TT (treatment with triple therapy after H. pylori challenge).