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. 2022 Aug 2;14(9):e15687. doi: 10.15252/emmm.202215687

Figure EV2. Four clusters of myeloid cells in the colon lamina propria (CLP) of IBD patients and effects of SOCE inhibition.

Figure EV2

(Left) FlowSOM plot of merged FCS files from unstimulated IBD samples and samples treated with PMA/ionomycin ± 1 μM BTP2 (non‐inflamed: n = 4, CD: n = 6, UC: n = 6). Colors indicate myeloid cell clusters within CD45+CD3 LPMCs. (Right) viSNE plots of one exemplary CD patient. Colors indicate expression levels of cell surface markers (blue: low; red: high) in cells left unstimulated, stimulated with PMA/ionomycin or stimulated in the presence of 1 μM BTP2.