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. 2022 Aug 24;13:921119. doi: 10.3389/fendo.2022.921119

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Copyright © 2022 Lv, Liu, Su, Gu, Fang, Fan, Gao, Ruan and Feng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Acupuncture treatment ameliorates gut barrier, gut inflammation and neuroinflammation in CRF mice after chemotherapy for BC. (A, B) The expression levels of tight junction proteins ZO-1, Occludin, and Claudin 5 in gut. (C, D) The expression levels of pro-inflammatory factors IL-1β, IL-6, and TNF-α in the gut. (E, F) The expression levels of pro-inflammatory factors IL-1β, IL-6, and TNF-α in the hippocampus. n = 3 mice in each group. **P < 0.01 versus control group; ^# P < 0.05 versus model group, ^## P < 0.01 versus model group; ^△ P < 0.05 versus sham group, ^△△ P < 0.01 versus sham group.