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. 2022 Aug 24;9:939837. doi: 10.3389/fmolb.2022.939837

FIGURE 2.

FIGURE 2

OPSL-DA results of metabolic parameters in the “Newborn-screen Group” and “Clinical diagnosed Group.” (A) Score plot of OPSL-DA. The x-axis represents the forecasting principal component and the y-axial represents the orthogonal principal component. Each point in the figure represents a sample. Red is for the “Clinical diagnosed Group” and green is for the “Newborn-screen Group.” (B) Inertia column diagram shows R2X, R2Y, and Q2 to evaluate whether the orthogonal components are sufficient. Q2 > 0.5 is considered to be reliable. (C) VIP scores of the different indicators are screened. Generally, the VIP value greater than 1 is screened as an important indicator (the 16 indicators are sorted in descending order). (D) Model validation diagram. The x-axis represents values of R2X, R2Y, and Q2, while the y-axial represents frequency of the model classification effect. The p-value is less than 0.01 which indicates the model is relatively good.