Table 3. RSV and Related Metabolites Determined by GC–MS in Urine* and Feces After RSV Intake (n = 195) and (or) Fecal Cultures After Individual Incubation of RSV, DHRSV, LUNU, PINO, DHP, DHST, and 4HST (n = 12)a.
| N° | compound | RT (min) | mass | target ion | LOD; LOQ (nM) | occurrence | urine (μg/mg creatinine)b | feces (μg/g)b |
|---|---|---|---|---|---|---|---|---|
| silylated | ||||||||
| 1 | DHP | 28.0 | 267 | 267 | 200; 500 | ND | ||
| 2 | 4HST | 28.1 | 268 | 268 | 200; 500 | ND | ||
| 3 | LUNU | 29.3 | 358 | 179 | 50; 100 | U, F, FC | 88.2 ± 121.2 | 32.5 ± 28.7 |
| 4 | PINO | 31.3 | 356 | 356 | 100; 250 | ND | ||
| 5 | cis-RSV | 32.0 | 444 | 444 | U | 274.0 ± 145.1c | ||
| 6 | DHRSV | 32.4 | 446 | 179 | 100; 250 | U, F, FC | 915.3 ± 654.8 | 34.1 ± 51.5 |
| 7 | DHST | 32.9 | 356 | 356 | 200; 500 | U, F | 11.2 ± 5.1 | D |
| 8 | RSV | 38.2 | 444 | 444 | 100; 250 | U, F, FC | 472.5 ± 269.0 | 1.4 ± 2.8 |
| non-silylated | ||||||||
| 1′ | 3HDB | 21.8 | 198d | 107 | 200; 500 | ND | ||
| 2′ | 4HDB | 22.1 | 198d | 107 | 100; 250 | U, FC | 13.2 ± 30.5 | |
U, urine; F, feces; FC, fecal culture; ND, not detected; D, detected but not quantified. *Hydrolyzed samples. 4HST, 4-hydroxy-trans-stilbene; LUNU, lunularin; DHRSV, dihydroresveratrol; DHST, 3,4′-dihydroxy-trans-stilbene; RSV (trans-resveratrol); 3HDB, 3-hydroxydibenzyl; 4HDB, 4-hydroxydibenzyl.
Mean ± SD.
Tentatively quantified as RSV.
Mass without silylation.