Table 2. Allelic and genotypic frequencies in control and AA patients.
Gene | SNP | Allele/genotype | AA patients n (%) | Contro n (%) | p-value |
---|---|---|---|---|---|
IL16 | rs17875486 | C | 192 (63.2) | 177 (59.8) | 0.39 |
T | 112 (36.8) | 119 (40.2) | |||
CC | 65 (42.8) | 52 (35.1) | 0.30 | ||
CT | 62 (40.8) | 73 (49.3) | |||
TT | 25 (16.4) | 23 (15.5) | |||
rs17875491 | G | 232 (76.8) | 229 (77.9) | 0.87 | |
C | 70 (23.2) | 65 (22.1) | |||
CC | 12 (7.9) | 4 (2.7) | 0.06 | ||
GC | 46 (30.3) | 57 (38.8) | |||
GG | 93 (61.2) | 86 (58.5) | |||
rs11073001 | A | 225 (74.0) | 206 (70.5) | 0.01 | |
G | 79 (26.0) | 86 (29.5) | |||
AA | 89 (58.6) | 76 (52.1) | 0.50 | ||
AG | 47 (30.9) | 54 (37.0) | |||
GG | 16 (10.5) | 16 (11.0) | |||
rs1803275 | G | 287 (95.0) | 277 (93.6) | 0.24 | |
A | 15 (5.0) | 19 (6.4) | |||
AA | 1 (0.7) | 1 (0.7) | 0.71 | ||
GA | 13 (8.6) | 17 (11.5) | |||
GG | 137 (90.1) | 130 (87.8) | |||
IL18 | rs187238 | C | 232 (76.8) | 224 (74.0) | 0.45 |
G | 70 (23.2) | 78 (26.0) | |||
CC | 91 (59.9) | 86 (57.3) | 0.66 | ||
CG | 50 (32.9) | 50 (33.3) | |||
GG | 10 (6.6) | 14 (9.3) | |||
rs1946518 | G | 178 (58.6) | 167 (56.8) | 0.64 | |
T | 126 (41.4) | 127 (43.2) | |||
GG | 50 (32.9) | 47 (32.0) | 0.84 | ||
GT | 78 (51.3) | 73 (49.7) | |||
TT | 24 (15.8) | 27 (18.4) | |||
rs549908 | T | 230 (76.2) | 220 (74.8) | 0.21 | |
G | 72 (23.8) | 74 (25.2) | |||
GG | 10 (6.6) | 12 (8.2) | 0.88 | ||
TG | 52 (34.2) | 50 (34.0) | |||
TT | 89 (58.6) | 85 (57.8) | |||
IL12B | rs3212227 | T | 204 (67.1) | 205 (69.3) | 0.69 |
G | 100 (32.9) | 91 (30.7) | |||
GG | 18 (11.8) | 14 (9.5) | 0.79 | ||
TG | 64 (42.1) | 63 (42.6) | |||
TT | 70 (46.1) | 71 (48.0) | |||
IL13 | rs848 | C | 227 (75.7) | 213 (72.4) | 0.07 |
A | 73 (24.3) | 81 (27.6) | |||
AA | 13 (8.6) | 13 (8.8) | 0.52 | ||
AC | 47 (30.9) | 55 (37.4) | |||
CC | 90 (59.2) | 79 (53.7) | |||
IL17A | rs2275913 | G | 215 (70.7) | 219 (74.5) | 0.53 |
A | 89 (29.3) | 75 (25.5) | |||
AA | 15 (9.9) | 13 (8.8) | |||
GA | 59 (38.8) | 49 (33.3) | |||
GG | 78 (51.3) | 85 (57.8) |
AA: Alopecia areata; SNP: single nucleotide polymorphism.