Table 3. Genetic haplotype frequencies estimation of IL16 and IL18 genes.
| Gene | SNP | Model | Genotype | AA cases n (%) |
Controls n (%) |
OR (95% CI) | p-value |
|---|---|---|---|---|---|---|---|
| IL16 | rs17875491 | Codominant | G/G | 93 (61.6) | 86 (58.5) | 1.00 | 0.06 |
| G/C | 46 (30.5) | 57 (38.8) | 0.75 (0.46–1.21) | ||||
| C/C | 12 (8.0) | 4 (2.7) | 2.77 (0.86–8.93) | ||||
| Dominant | G/G | 93 (61.6) | 86 (58.5) | 1.00 | 0.59 | ||
| G/C-C/C | 58 (38.4) | 61 (41.5) | 0.88 (0.55–1.40) | ||||
| Recessive | G/G-G/C | 139 (92) | 143 (97.3) | 1.00 | 0.04 | ||
| C/C | 12 (8.0) | 4 (2.7) | 3.09 (0.97–9.80) |
SNP: single nucleotide polymorphism; AA: Alopecia areata; OR: odds ratio.