Table 2.
Breast biopsy patterns* after 524,860 screening mammograms in the Breast Cancer Surveillance Consortium, 1999–2010
| No biopsy | At least 1 biopsy | Fine needle aspiration | Core biopsy | Surgical biops | At least 2 types of biopsies | |
|---|---|---|---|---|---|---|
| Characteristics at screen | N (row %) | N (row %) | N (row %) | N (row %) | N (row %) | N (row %) |
| Total N (%) | 516930 (98.5) | 7930 (1.5) | 819 (0.2) | 5589 (1.1) | 3422 (0.7) | 1805 (0.3) |
| Days to first biopsy or FNA (median, interquartile range) | 29 (18, 55) | 37 (18, 144) | 27 (16, 45) | 49 (31, 86) | ||
| Charlson Comorbidity Score, N (%) | ||||||
| 0 | 374461 (98.6) | 5497 (1.4) | 603 (0.2) | 3865 (1.0) | 2405 (0.6) | 1302 (0.3) |
| 1 | 104170 (98.4) | 1719 (1.6) | 151 (0.1) | 1222 (1.2) | 710 (0.7) | 350 (0.3) |
| ≥2 | 38299 (98.2) | 714 (1.8) | 65 (0.2) | 502 (1.3) | 307 (0.8) | 153 (0.4) |
| Age group, years, N (%) | ||||||
| 66–74 | 299614 (98.4) | 4720 (1.6) | 479 (0.2) | 3365 (1.1) | 1959 (0.6) | 1021 (0.3) |
| 75–84 | 187390 (98.5) | 2790 (1.5) | 291 (0.2) | 1926 (1.0) | 1268 (0.7) | 668 (0.4) |
| 85–94 | 29926 (98.6) | 420 (1.4) | 49 (0.2) | 298 (1.0) | 195 (0.6) | 116 (0.4) |
| Race/ethnicity, N (%) | ||||||
| White | 414722 (98.5) | 6440 (1.5) | 675 (0.2) | 4572 (1.1) | 2810 (0.7) | 1534 (0.4) |
| Black | 40511 (98.8) | 489 (1.2) | 40 (0.1) | 306 (0.7) | 210 (0.5) | 65 (0.2) |
| Hispanic | 6426 (98.3) | 113 (1.7) | 18 (0.3) | 80 (1.2) | 45 (0.7) | 27 (0.4) |
| Asian/Pacific Islander | 14833 (98.6) | 210 (1.4) | 32 (0.2) | 148 (1.0) | 96 (0.6) | 63 (0.4) |
| Other | 5645 (98.4) | 90 (1.6) | 6 (0.1) | 65 (1.1) | 47 (0.8) | 25 (0.4) |
| Missing | 34793 (98.3) | 588 (1.7) | 48 (0.1) | 418 (1.2) | 214 (0.6) | 91 (0.3) |
| Education, N (%) | ||||||
| <High School Graduate | 62273 (98.7) | 839 (1.3) | 74 (0.1) | 503 (0.8) | 444 (0.7) | 170 (0.3) |
| High School Graduate or GED | 148232 (98.4) | 2343 (1.6) | 242 (0.2) | 1625 (1.1) | 1066 (0.7) | 557 (0.4) |
| Some College or Technical School | 110077 (98.4) | 1795 (1.6) | 200 (0.2) | 1290 (1.2) | 777 (0.7) | 449 (0.4) |
| College Graduate | 110405 (98.3) | 1915 (1.7) | 232 (0.2) | 1376 (1.2) | 840 (0.7) | 510 (0.5) |
| Missing | 85943 (98.8) | 1038 (1.2) | 71 (0.1) | 795 (0.9) | 295 (0.3) | 119 (0.1) |
| Median income, N (%) | ||||||
| ≤$36,000 | 46114 (98.5) | 720 (1.5) | 63 (0.1) | 478 (1.0) | 316 (0.7) | 127 (0.3) |
| $36001–$47500 | 73759 (98.5) | 1102 (1.5) | 86 (0.1) | 713 (1.0) | 521 (0.7) | 211 (0.3) |
| $47501–$64600 | 104368 (98.4) | 1696 (1.6) | 183 (0.2) | 1210 (1.1) | 759 (0.7) | 429 (0.4) |
| ≥$64601 | 120603 (98.1) | 2280 (1.9) | 263 (0.2) | 1770 (1.4) | 855 (0.7) | 586 (0.5) |
| Missing | 172086 (98.8) | 2132 (1.2) | 224 (0.1) | 1418 (0.8) | 971 (0.6) | 452 (0.3) |
| Rurality, N (%) | ||||||
| Urban focused | 284394 (98.5) | 4237 (1.5) | 441 (0.2) | 3132 (1.1) | 1677 (0.6) | 965 (0.3) |
| Large rural | 107159 (98.4) | 1718 (1.6) | 181 (0.2) | 1152 (1.1) | 796 (0.7) | 392 (0.4) |
| Small rural | 61966 (98.5) | 946 (1.5) | 81 (0.1) | 617 (1.0) | 435 (0.7) | 181 (0.3) |
| Isolated rural | 51457 (98.5) | 765 (1.5) | 87 (0.2) | 476 (0.9) | 408 (0.8) | 190 (0.4) |
| Missing | 11954 (97.8) | 264 (2.2) | 29 (0.2) | 212 (1.7) | 106 (0.9) | 77 (0.6) |
| Body mass index, N (%), kg/m2 | ||||||
| <25 | 92796 (98.3) | 1562 (1.7) | 203 (0.2) | 1122 (1.2) | 671 (0.7) | 411 (0.4) |
| 25 to <30 | 71445 (98.2) | 1277 (1.8) | 164 (0.2) | 941 (1.3) | 537 (0.7) | 346 (0.5) |
| 30 to <35 | 32834 (97.9) | 703 (2.1) | 66 (0.2) | 550 (1.6) | 294 (0.9) | 198 (0.6) |
| ≥35 | 15748 (97.7) | 377 (2.3) | 47 (0.3) | 274 (1.7) | 182 (1.1) | 116 (0.7) |
| Missing | 304107 (98.7) | 4011 (1.3) | 339 (0.1) | 2702 (0.9) | 1738 (0.6) | 734 (0.2) |
| Breast density, N (%) | ||||||
| Almost entirely fat | 50370 (99.0) | 525 (1.0) | 45 (0.1) | 390 (0.8) | 230 (0.5) | 135 (0.3) |
| Scattered fibroglandular densities | 243242 (98.7) | 3223 (1.3) | 283 (0.1) | 2313 (0.9) | 1317 (0.5) | 662 (0.3) |
| Heterogenously dense | 148802 (98.3) | 2610 (1.7) | 273 (0.2) | 1818 (1.2) | 1151 (0.8) | 592 (0.4) |
| Extemely dense | 15022 (98.3) | 261 (1.7) | 34 (0.2) | 162 (1.1) | 125 (0.8) | 58 (0.4) |
| Missing | 59494 (97.8) | 1311 (2.2) | 184 (0.3) | 906 (1.5) | 599 (1.0) | 358 (0.6) |
| Family history of breast cancer, N (%) | ||||||
| No | 376568 (98.5) | 5832 (1.5) | 620 (0.2) | 4160 (1.1) | 2458 (0.6) | 1336 (0.3) |
| Yes | 86648 (98.1) | 1635 (1.9) | 158 (0.2) | 1189 (1.3) | 745 (0.8) | 434 (0.5) |
| Missing | 53714 (99.1) | 463 (0.9) | 41 (0.1) | 240 (0.4) | 219 (0.4) | 35 (0.1) |
| Time since prior mammogram, N (%) | ||||||
| No prior | 4577 (96.2) | 179 (3.8) | 17 (0.4) | 102 (2.1) | 85 (1.8) | 24 (0.5) |
| 1 year | 5083 (97.7) | 120 (2.3) | 22 (0.4) | 68 (1.3) | 61 (1.2) | 30 (0.6) |
| 1–2 years | 463251 (98.6) | 6540 (1.4) | 688 (0.1) | 4628 (1.0) | 2833 (0.6) | 1525 (0.3) |
| ≥3 years | 31346 (97.5) | 820 (2.5) | 66 (0.2) | 599 (1.9) | 351 (1.1) | 189 (0.6) |
| Missing | 12673 (97.9) | 271 (2.1) | 26 (0.2) | 192 (1.5) | 92 (0.7) | 37 (0.3) |
| History of breast biopsy or aspiration, N (%) | ||||||
| No | 378199 (98.7) | 5051 (1.3) | 503 (0.1) | 3629 (0.9) | 2144 (0.6) | 1161 (0.3) |
| Yes | 131226 (97.9) | 2774 (2.1) | 302 (0.2) | 1893 (1.4) | 1229 (0.9) | 620 (0.5) |
| Missing | 7505 (98.6) | 105 (1.4) | 14 (0.2) | 67 (0.9) | 49 (0.6) | 24 (0.3) |
*
Biopsy patterns are based on biopsies found within 12 months after screening exam and prior to next screen. If multiple biopsy types are found after a single screen the screen would appear in multiple columns.
FNA: Fine Needle Aspiration.