Table 1.
Cohort characteristics for all subjects and stratified by baseline knee OA status
| Baseline Demographics | MOST | Chingford | JoCoOA | Framingham | HCS | TaSOAC | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Follow-up period | 5 years | 9 years | 7 years | 7 years | 12 years | 5 years | ||||||||||||
| Original N | 3026 | 1003 | 2754 | 1166 | 1412 | 1100 | ||||||||||||
| ROA | OA-related Knee Pain | PROA | ROA | OA-related Knee Pain | PROA | ROA | OA-related Knee Pain | PROA | ROA | OA-related Knee Pain | PROA | ROA | OA-related Knee Pain | PROA | ROA | OA-related Knee Pain | PROA | |
| N | 1078 | 1102 | 1,518 | 681 | 556 | 756 | 997 | 795 | 1213 | 759 | 629 | 789 | 337 | 243 | - | - | 452 | - |
| Knee OA outcome at follow-up, n (%) | 262 (24.3) | 322 (29.2) | 308 (20.3) | 190 (27.9) | 65 (11.7) | 48 (6.4) | 255 (25.6) | 131 (16.5) | 132 (10.9) | 70 (9.2) | 116 (18.4) | 48 (6.1) | 114 (33.8) | 21 (8.6) | - | - | 60 (13.3) | - |
| MET days/week, median (IQR) | 1.2 (0.6–1.9) | 1.1 (0.6–1.9) | 1.1 (0.6–1.9) | 0 (0–0.5) | 0 (0–0.5) | 0 (0–0.5) | 0.3 (0.0–0.8) | 0.3 (0.1–0.8) | 0.3 (0.0–0.8) | 11.4 (8.7–14.4) | 11.4 (8.7–14.4) | 11.3 (8.4–14.3) | 0.2 (0–0.5) | 0.2 (0–0.5) | - | - | 1.4 (0.3–2.8) | - |
| Age (years), mean (48) | 60.5 (7.7) | 62.3 (7.9) | 61.6 (7.9) | 53.5 (5.8) | 53.8 (5.9) | 53.7 (5.9) | 60.7 (8.5) | 61.9 (9.3) | 61.7 (9.0) | 51.9 (8.7) | 51.9 (8.7) | 51.9 (8.7) | 64.7 (2.7) | 64.8 (2.8) | - | - | 62.0 (7.0) | - |
| Sex, n (% Female) | 638 (59.2) | 608 (55.2) | 890 (58.6) | 681 (100) | 556 (100) | 756 (100) | 673 (67.5) | 507 (63.8) | 802 (66.1) | 427 (56.3) | 348 (55.3) | 442 (56.0) | 170 (50.5) | 117 (48.2) | - | - | 219 (48.5) | - |
| Race, n (%) | ||||||||||||||||||
| Caucasian | 945 (87.7) | 969 (87.9) | 1325 (87.3) | 681 (100) | 556 (100) | 756 (100) | 731 (73.3) | 577 (72.6) | 879 (72.5) | 759 (100) | 629 (100) | 789 (100) | 337 (100) | 243 (100) | - | - | 446 (98.7) | - |
| African American | 117 (10.8) | 118 (10.7) | 169 (11.1) | - | - | - | 266 (26.7) | 218 (27.4) | 334 (27.5) | - | - | - | - | - | - | - | - | - |
| Chinese | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other | 16 (1.5) | 15 (1.4) | 24 (1.6) | - | - | - | - | - | - | - | - | - | - | - | - | - | 6 (1.3) | - |
| BMI (kg/m2), mean (48) | 29.1 (4.7) | 29.6 (4.8) | 29.5 (5.0) | 25.1 (3.9) | 25.0 (3.9) | 25.3 (4.0) | 29.4 (5.5) | 29.5 (5.8) | 29.6 (5.8) | 27.0 (4.8) | 26.8 (4.6) | 27.1 (4.8) | 26.5 (4.0) | 26.3 (4.0) | - | - | 27.2 (4.2) | - |
*
Subjects not having knee osteoarthritis outcome at baseline, not having rheumatoid arthritis, not missing knee osteoarthritis data at baseline or follow-up, not missing PA, age, sex, race, BMI data