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. 2022 Aug 28;37:71–77. doi: 10.1016/j.ctro.2022.08.013

Table 4.

Clinical and DVH Cut-off Parameters for Worsening Cosmesis.

Variable OR p-value
Age 1.11 (0.94 – 1.01) 0.23
BMI 0.90 (0.74–1.10) 0.31
Axillary Dissection vs SLNBx 1.79 (0.27 – 11.86) 0.55
Laterality - Right vs Left 0.20 (0.02 – 1.91) 0.16
Histologic Grade (Ref = Grade 1)
Grade 2 2.44 (0.23 – 26.29) 0.41
Grade 3 8.66 (0.58–130.07) 0.56
Hormonal Therapy (Ref = None)
Tamoxifen 3.00 (0.18 – 50.79) 0.26
AI 1.00 (0.15 – 6.91) 0.91
Bra Cup Size ≥ D 2.43 (0.38 – 15.27) 0.34
Tumor Size (cm) 1.52 (0.46 – 5.00) 0.49
PTV D95% 1.20 (0.43 – 3.39) 0.73
PTV Max Dose 1.06 (0.67 – 1.68) 0.80
Lung V10Gy 1.95 (0.72 – 5.25) 0.19
Breast V20Gy 1.22 (1.03 – 1.44) 0.02
Breast V40Gy 1.26 (1.03 – 1.54) 0.03
Breast V20Gy ≥ 30.48 % 15.00 (1.52 – 148.31) 0.02
Breast V40Gy ≥ 19.48 % 15.00 (1.52 – 148.31) 0.02

Note: BMI = body-mass index; SLNBx = sentinel lymph node biopsy Ref = reference; AI = aromatase inhibitor; PTV = planning target volume; Gy = Gray.

Bold denotes statistical significance.