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. 2022 Sep 6;21:178. doi: 10.1186/s12933-022-01612-7

Table 1.

Clinical characteristics of study participants divided into offspring of mothers without diabetes (controls) and offspring of mothers with type 1 diabetes (cases)

Controls n = 84 Cases n = 75 P-value
Age (years), mean (SD) 20.6 (1.6) 20.5 (1.6) 0.77
BMI (kg/m2), mean (SD) 24.1 (4.8) 24.5 (5.0) 0.64
Body fat percentage (%), mean (SD)
 Women 30.1 (9.2) 32.9 (7.7) 0.099
 Men 18.4 (8.0) 19.3 (10.8) 0.72
BP (mmHg), mean (SD)
 Systolic 119 (11) 117 (12) 0.23
 Diastolic 74 (7) 74 (9) 0.66
Comorbidity, n (%)
 Asthma 11 (13) 9 (12) 0.89
 Atopy 7 (8) 10 (14) 0.28
 Cardiovascular disease 4 (5) 5 (7) 0.73
 Inflammatory bowel disease 3 (4) 7 (10) 0.19
 Mental and behavioral diseases 18 (21) 11 (15) 0.31
 Neurologic diseases 10 (12) 12 (16) 0.41
 Psoriasis 1 (1) 3 (4) 0.34
 Rheumatic diseases 2 (2) 0 (0) 0.50
Fasting insulin (mU/L), mean (SD) 10.6 (6.5) 11.2 (9.1) 0.65
Glucose (mmol/l), mean (SD)
 0-h 5.40 (0.43) 5.39 (0.41) 0.84
 2-h 5.62 (1.43) 5.85 (1.64) 0.34
HbA1c (mmol/mol; %), mean (SD) 33 (2); 5.13 (0.20) 33 (3); 5.15 (0.25) 0.54
High sensitivity C-reactive protein (mg/L), mean (SD) 1.4 (1.9) 2.0 (4.9) 0.56
LTPA (MET-h/week), median (IQR) 24.3 (11.6, 41.3) 24.1 (13.8, 34.7) 0.89
Mean arterial pressure (mmHg), mean (SD) 89 (7) 88 (9) 0.41
Pulse pressure (mmHg), mean (SD) 45 (8) 43 (9) 0.26
Pulse rate (bpm), mean (SD) 76 (12) 75 (12) 0.74
Smoking, n (%)
 No 62 (74) 60 (80) 0.50
 Occasionally 12 (14) 10 (13)
 Continuously 10 (12) 5 (7)
Total cholesterol (mmol/L), mean (SD) 4.31 (0.65) 4.40 (0.75) 0.41
LDL (mmol/L), mean (SD) 2.56 (0.66) 2.59 (0.70) 0.73
HDL (mmol/L), mean (SD)
 Women 1.65 (0.38) 1.68 (0.39) 0.70
 Men 1.38 (0.30) 1.45 (0.32) 0.37
Triglycerides (mmol/l), mean (SD)
 Women 0.97 (0.48) 0.94 (0.62) 0.81
 Men 0.94 (0.35) 0.85 (0.34) 0.39
Women, n (%) 55 (65) 50 (67) 0.87

LTPA leisure-time physical activity, MET-h Metabolic equivalent of task-hours, SD standard deviation