Fig. 7.

The circ_0000098/miR-383/MCUR1 signaling modulates HCC development in vivo. A Schematic illustration of the treatment regimen. B Immunohistochemical images and HE staining images of tumors. C HE staining images of lungs, spleens, and hearts. D-G ALT (D), AST (E), ALP (F), and AFP (G) levels were measured in the indicated groups. H-J RT-qPCR assays were used to detect circ_0000098 (H), miR-383 (I), and MCUR1 (J) expression in the indicated groups. K-L Detection of ATP levels (K) and P-gp expression (L) in the indicated groups. M Western blotting analysis of P-gp expression in the indicated groups. *P < 0.05, **P < 0.01