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. 2022 Sep 7;9:546. doi: 10.1038/s41597-022-01640-8

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© The Author(s) 2020, corrected publication 2023

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Fig. 1 — Diagram illustrating the sequential steps leading to the delineation of spatial signatures. From a series of enclosing components, to enclosures, enclosed tessellation (ET), the addition of form and function characters to ET cells, and the development of spatial signatures.