Table 4.
Metagenomic Kp strain-level detection performed using StrainGST in a Kp-spiked mock microbiome sample.
| Spiked Microbiome |
StrainGST result |
|||||
|---|---|---|---|---|---|---|
| Mock | Spiked strain(s) | Spiked abundance (%) | Strain(s) detected | Strain est. abundance (%) | Total est. abundance (%) | Confidence Score |
| M1 | none | NA | ND | 0 | 0 | NA |
| M2 | ST11 | 0.001 | ND | 0 | 0 | NA |
| M3 | ST11 | 0.01 | ND | 0 | 0 | NA |
| M4 | ST11 | 0.1 | ST12a, ST11 | 0.051, 0.166 | 0.217 | 0.207, 0.044 |
| M5 | ST11 | 1.0 | ST11, ST340a | 0.429, 0.762 | 1.191 | 0.760, 0.027 |
| M6 | ST11, ST697b | 1:1 | ST11, ST697, ST340a | 0.798, 0.377, 0.756 | 1.93 | 0.705, 0.591, 0.03 |
aST340 and ST12 are single and double locus variants of ST11, respectively
bKlebsiella variicola
NA = not applicable
ND = not detected.