3. Assessment of items relating to applicability of trial findings.
Clearly defined study population? | Interventions sufficiently described? | Main outcomes sufficiently described? | Appropriate timing of outcome measurement? (Yes ≥ 6 months) | Assessment of compliance with interventions | |
Baker 1991 | Yes | Partial: frequency and intensity of gait retraining not described | Yes | No: only followed up until discharge: mean stay in rehabilitation hospital for intervention group was 54 days. | No: although mention of treadmill participants aiming to exceed previous performance on the treadmill |
Binder 2004 | Yes | Yes | Yes | Partial: although 6 months follow‐up, it was only until the end of the intervention. | Yes: in both groups |
Bischoff‐Ferrari 2010 | Yes | Yes | Yes | Yes | Yes |
Braid 2008 | Yes | Partial: usual post‐discharge physiotherapy not described | Yes | Partial: 14 weeks. Intervention ended after 6 weeks. | Partial: compliance and tolerance to electrical stimulation only reported for intervention group |
Gorodetskyi 2007 | Yes | Yes | Yes (although limited) | No: 10 days marking end of treatment. | Yes: it is stated that intervention was received by all participants |
Graham 1968 | Partial: inadequate description; excluded post‐randomisation if unsuitable to walk at 2 weeks | Partial: little description of rehabilitation | Partial: no record of mobility outcomes | Yes: 1 year | No |
Hauer 2002 | Yes | Yes | Partial: however, clarification on some outcome measures was obtained via contact with trial author | Yes: 6 months (3 months after the end of the intervention). Two year follow‐up results reported for whole study population | Yes: in both groups |
Karumo 1977 | Partial: no mention of exclusion criteria. Though the inclusion criteria were a displaced femoral neck fracture, the implants used for some participants (9 Jewett nails, 1 Rush nail, 1 Kuntscher nail) suggest that some extracapsular fractures were included. | Yes | Partial: incomplete descriptions | No: 9 weeks only for function (3 months for mortality) | No |
Kimmel 2016 | Yes | Yes | Yes | No: length of follow‐up is Day 5 or discharge if discharged before Day 5 | No |
Kronborg 2017 | Yes | Yes | Yes | No: 10 days or discharge if sooner | Yes: in both groups |
Lamb 2002 | Yes | Yes | Yes | Partial: 13 weeks from surgery. | Yes: “All of the women used their stimulators for more than 75% of the cumulative time requested” |
Langford 2015 | Yes | Yes | Yes | Partial | No |
Latham 2014 | Yes | Yes | Yes | Partial: 9 months | Yes: compliance with interventions assessed: "adherence was 98%” |
Lauridsen 2002 | Yes | Yes | Yes | No: primary outcome = length of training period; otherwise until discharge | Yes: in terms of the interventions (although not the components) |
Magaziner 2019 | Yes | Yes | Yes | Partial: 40 weeks | Yes |
Mangione 2005 | Yes | Yes | Yes | No: 12 weeks for the two intervention groups but 8 weeks only for the control group. | Partial: only compliance of the intervention groups recorded |
Mangione 2010 | Yes | Yes | Yes | Partial: majority followed up for 16 weeks | Yes |
Miller 2006 | Yes | Yes | Yes | Partial: 12 weeks only for mobility outcomes. One year follow‐up data for mortality, re‐admissions and admission to higher level of care | Partial: only compliance of the intervention groups recorded |
Mitchell 2001 | Yes | Yes | Yes | Partial: 16 weeks follow‐up. Intervention ended at 6 weeks | Partial: only compliance with intervention recorded |
Monticone 2018 | Yes | Partial: dosage about open kinetic chain exercises in the control group not described | Yes | Partial | Yes: “Physiotherapists’ systematic checking of the exercise administration manual revealed excellent compliance rates in both groups". |
Moseley 2009 | Yes | Yes | Yes | Partial: 16 weeks follow‐up. | Yes: “Participants completed exercise diaries which were analysed to ascertain adherence to the programmes.” Care provider visits also documented |
Oh 2020 | Yes | Yes | Yes | Partial: 6 months follow‐up (5 months after the end of intervention) | No |
Ohoka 2015 | Yes | No: standard physical therapy not described. Intensity of treadmill training not described | Yes | Partial: average of approximately 6 months | No |
Oldmeadow 2006 | Yes | Yes | Yes | No: only until acute hospital discharge. Mobility outcomes at 7 days | Yes: time to first walk recorded in both groups |
Orwig 2011 | Yes | Yes | Yes | Yes. Outcomes were assessed at 2, 6, and 12 months after hip fracture | Yes. Hours spent exercising quantified |
Pol 2019 | Yes | Yes | Yes | Partial | Yes |
Resnick 2007 | Yes | Yes | Yes | No: although follow‐up was 12 months from fracture, this coincided with the end of treatment | Partial: no data for usual care group |
Salpakoski 2015 | Yes | Partial: control standard care did not have specific dosage for the exercise “5‐7 exercises for the lower limbs” | Yes | Partial | Partial: only compliance in intervention group reported but reported “None of the participants were followed for compliance” in control |
Sherrington 1997 | Yes | Partial: "Usual care" not described | Yes | No: final assessment at 1 month (27 to 43 days) | Partial: only the intervention group completed diaries and were asked about the specific exercises. However, all participants were asked about general exercise. |
Sherrington 2003 | Yes | Yes | Yes | No: 2 weeks follow‐up only | Partial: some data available but not regarding weight bearing |
Sherrington 2004 | Yes | Yes | Yes | Partial: 4 months follow‐up only | Partial: compliance data collected for the two exercise groups but not for the control group. |
Sherrington 2020 | Yes | Yes | Yes | Yes: 12 months | Partial: compliance data collected for intervention group via diaries |
Stasi 2019 | Yes | Yes | No | Partial: 6 months | No |
Suwanpasu 2014 | No | No | Unclear | No: 6 weeks after discharge | No |
Sylliaas 2011 | Yes | Yes | Yes | No: intervention is only 12 weeks following an observation period of 12 weeks | No: not assessed |
Sylliaas 2012 | Yes | Yes | Yes | Partial: although is 36 weeks after fracture, trial 1 starts 12 weeks after fracture, final follow‐up is 24 weeks after start of 2011 intervention | No: not assessed |
Taraldsen 2019 | Yes | Yes | Yes | Yes: T3 = 48 to 56 weeks | Yes |
Tsauo 2005 | Yes | Yes | Yes | Yes: 6 months' follow‐up. | No. However, 4 participants in the intervention group were excluded because of poor compliance. |
Van Ooijen 2016 | Yes | Yes | Yes | Partial: 12 months' follow‐up for some but not all outcomes | No, included in protocol bot not reported |
Williams 2016 | Yes | Yes | Yes | No: 3 months | No |