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. 2022 Sep 7;2022(9):CD001704. doi: 10.1002/14651858.CD001704.pub5

Comparison 4. Post‐hospital rehabilitation: mobilisation strategy versus control, critical outcomes.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
4.1 Mobility (measured using mobility scales): combined data for all strategy types 7 761 Std. Mean Difference (IV, Random, 95% CI) 0.32 [0.11, 0.54]
4.2 Mobility (measured using Timed Up and Go, seconds): combined data for all strategy types 3 375 Mean Difference (IV, Fixed, 95% CI) ‐1.98 [‐5.59, 1.63]
4.3 Mobility (measured using 6‐Minute Walk Test, metres): combined data for all strategy types 4 396 Mean Difference (IV, Fixed, 95% CI) 28.66 [10.88, 46.44]
4.4 Mobility (measured using mobility scales): gait, balance and function 5 621 Std. Mean Difference (IV, Fixed, 95% CI) 0.20 [0.05, 0.36]
4.5 Mobility (measured using Timed Up and Go, seconds): gait, balance and function 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.6 Mobility (measured using Timed Up and Go, seconds): resistance/strength training 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.7 Mobility (measured using 6‐Minute Walk Test, metres): resistance/strength training 3 198 Mean Difference (IV, Fixed, 95% CI) 55.65 [28.58, 82.72]
4.8 Mobility (measured using 6‐Minute Walk Test, metres): endurance training 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.9 Mobility (measured using mobility scales): multiple component 2 104 Std. Mean Difference (IV, Fixed, 95% CI) 0.94 [0.53, 1.34]
4.10 Mobility (measured using 6‐Minute Walk Test, metres): multiple component 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.11 Mobility (measured using mobility scales): other type of exercise (non‐weight bearing exercise) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.12 Mobility (measured using Timed Up and Go, seconds): other type of exercise OT +/‐ sensor) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.13 Mobility (measured using mobility scales) reporting individual outcome measures 14   Mean Difference (IV, Random, 95% CI) Subtotals only
4.13.1 Modified Physical Performance Test 1 80 Mean Difference (IV, Random, 95% CI) 5.70 [2.74, 8.66]
4.13.2 Physical Performance and Mobility Examination Score 1 105 Mean Difference (IV, Random, 95% CI) 0.32 [‐0.42, 1.05]
4.13.3 Short Physical Performance Battery 4 552 Mean Difference (IV, Random, 95% CI) 0.68 [0.15, 1.21]
4.13.4 Performance Oriented Mobility Assessment 1 24 Mean Difference (IV, Random, 95% CI) 4.90 [2.11, 7.69]
4.13.5 Timed Up and Go 3 366 Mean Difference (IV, Random, 95% CI) 1.69 [‐2.74, 6.12]
4.13.6 6 Minute Walk Test 4 396 Mean Difference (IV, Random, 95% CI) 33.98 [7.08, 60.89]
4.14 Mobility (measured using self‐report, continuous scales): combined data for all strategy types 2 355 Mean Difference (IV, Fixed, 95% CI) 1.46 [‐0.62, 3.53]
4.15 Mobility (measured using self‐reported, dichotomous outcome): combined data for all strategy types 1 108 Risk Ratio (M‐H, Fixed, 95% CI) 0.45 [0.29, 0.72]
4.16 Walking speed: combined data for all strategy types 14 1067 Std. Mean Difference (IV, Fixed, 95% CI) 0.16 [0.04, 0.29]
4.17 Walking speed: gait, balance and function 7 511 Std. Mean Difference (IV, Fixed, 95% CI) 0.08 [‐0.09, 0.25]
4.18 Walking speed: resistance/strength training 3 197 Std. Mean Difference (IV, Fixed, 95% CI) 0.29 [‐0.01, 0.58]
4.19 Walking speed: endurance 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.20 Walking speed: multiple component 3 285 Std. Mean Difference (IV, Random, 95% CI) 0.53 [‐0.13, 1.18]
4.21 Walking speed: other (post‐discharge physio telephone support and coaching) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.22 Walking speed: other (non‐weight bearing) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.23 Walking speed subgrouped by studies with cognitive impairment included v studies with cognitive impairment not included, combined data for all strategy types 14   Std. Mean Difference (IV, Fixed, 95% CI) Subtotals only
4.23.1 People with cognitive impairment included 2 304 Std. Mean Difference (IV, Fixed, 95% CI) 0.07 [‐0.16, 0.29]
4.23.2 People with cognitive impairment excluded 12 762 Std. Mean Difference (IV, Fixed, 95% CI) 0.19 [0.04, 0.34]
4.24 Walking speed: subgrouped by outpatient v secondary and social care setting 14   Std. Mean Difference (IV, Fixed, 95% CI) Subtotals only
4.24.1 Outpatient 2 229 Std. Mean Difference (IV, Fixed, 95% CI) 0.35 [0.08, 0.62]
4.24.2 Secondary and social care 12 838 Std. Mean Difference (IV, Fixed, 95% CI) 0.11 [‐0.02, 0.25]
4.25 Walking speed subgrouped by mean age ≤ 80 years v > 80 years, combined data for all strategies 14   Std. Mean Difference (IV, Fixed, 95% CI) Subtotals only
4.25.1 Mean age in study 80 years or less 8 536 Std. Mean Difference (IV, Fixed, 95% CI) 0.12 [‐0.05, 0.30]
4.25.2 Mean age in study > 80 years 6 530 Std. Mean Difference (IV, Fixed, 95% CI) 0.18 [0.01, 0.36]
4.26 Functioning (measured using functioning scales): combined data for all strategy types 9 936 Std. Mean Difference (IV, Fixed, 95% CI) 0.23 [0.10, 0.36]
4.27 Functioning (measured using functioning scales): gait, balance and function 4 432 Std. Mean Difference (IV, Fixed, 95% CI) 0.17 [‐0.02, 0.36]
4.28 Functioning (measured using functioning scales): resistance/strength training 2 246 Std. Mean Difference (IV, Fixed, 95% CI) 0.29 [0.03, 0.55]
4.29 Functioning (measured using functioning scales): multiple components 2 107 Std. Mean Difference (IV, Fixed, 95% CI) 0.34 [‐0.04, 0.72]
4.30 Functioning (measured using functioning scales): other: OT +/‐ sensor 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.31 Health‐related quality of life (measured using HRQoL scales): combined data for all strategy types 10 785 Std. Mean Difference (IV, Fixed, 95% CI) 0.14 [‐0.00, 0.29]
4.32 Health‐related quality of life (measured using HRQoL scales): gait, balance and function 4 316 Std. Mean Difference (IV, Random, 95% CI) 0.08 [‐0.37, 0.53]
4.33 Health‐related quality of life (measured using HRQoL scales): resistance/strength training 3 197 Std. Mean Difference (IV, Fixed, 95% CI) 0.15 [‐0.14, 0.45]
4.34 Health‐related quality of life (measured using HRQoL scales): endurance 1 22 Mean Difference (IV, Random, 95% CI) 9.50 [‐8.56, 27.56]
4.35 Health‐related quality of life (measured using HRQoL scales): multiple components 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.36 Health‐related quality of life subgrouped by studies with cognitive impairment included v studies with cognitive impairment not included, combined data for all strategy types 10   Std. Mean Difference (IV, Fixed, 95% CI) Subtotals only
4.36.1 People with cognitive impairment included 1 120 Std. Mean Difference (IV, Fixed, 95% CI) 0.00 [‐0.36, 0.36]
4.36.2 People with cognitive impairment excluded 9 665 Std. Mean Difference (IV, Fixed, 95% CI) 0.17 [0.01, 0.33]
4.37 Health‐related quality of life subgrouped by outpatient v secondary and social care setting 10   Std. Mean Difference (IV, Fixed, 95% CI) Subtotals only
4.37.1 Outpatient 2 233 Std. Mean Difference (IV, Fixed, 95% CI) 0.18 [‐0.09, 0.45]
4.37.2 Secondary and social care 8 552 Std. Mean Difference (IV, Fixed, 95% CI) 0.13 [‐0.04, 0.30]
4.38 Health‐related quality of life subgrouped by mean age ≤ 80 years v > 80 years, combined data for all strategy 10   Std. Mean Difference (IV, Fixed, 95% CI) Subtotals only
4.38.1 Mean age in study 80 years or less 4 184 Std. Mean Difference (IV, Fixed, 95% CI) 0.25 [‐0.05, 0.55]
4.38.2 Mean age in study > 80 years 6 601 Std. Mean Difference (IV, Fixed, 95% CI) 0.11 [‐0.05, 0.27]
4.39 Mortality, short term: combined data for all strategy types 7 737 Risk Ratio (M‐H, Fixed, 95% CI) 1.01 [0.49, 2.06]
4.40 Mortality, short term: gait, balance and function 3 264 Risk Ratio (M‐H, Fixed, 95% CI) 1.12 [0.46, 2.72]
4.41 Mortality, short term: resistance/strength training 2 123 Risk Ratio (M‐H, Fixed, 95% CI) 1.40 [0.19, 10.03]
4.42 Mortality, short term: multiple components 2 290 Risk Ratio (M‐H, Fixed, 95% CI) 0.61 [0.08, 4.55]
4.43 Mortality, short term: other: non‐weight bearing 1 60 Risk Ratio (M‐H, Fixed, 95% CI) 0.50 [0.03, 7.59]
4.44 Mortality, long term: combined data for all strategy types 4 588 Risk Ratio (M‐H, Fixed, 95% CI) 0.73 [0.39, 1.37]
4.45 Mortality, long term: gait, balance and function 2 254 Risk Ratio (M‐H, Fixed, 95% CI) 0.75 [0.34, 1.67]
4.46 Mortality, long term: multiple components 2 334 Risk Ratio (M‐H, Fixed, 95% CI) 0.70 [0.25, 1.96]
4.47 Adverse events (measured using dichotomous outcomes): combined data for all strategy types 4   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
4.47.1 Re‐admission 2 206 Risk Ratio (M‐H, Fixed, 95% CI) 0.86 [0.52, 1.42]
4.47.2 Re‐operation 1 173 Risk Ratio (M‐H, Fixed, 95% CI) 0.46 [0.20, 1.08]
4.47.3 Surgical complications 1 25 Risk Ratio (M‐H, Fixed, 95% CI) 0.92 [0.06, 13.18]
4.48 Adverse events (measured using re‐admission rate: combined for all strategy types 1   Rate Ratio (IV, Fixed, 95% CI) Totals not selected
4.49 Adverse events (measured using rate of falls): combined for all strategy types 3   Rate Ratio (IV, Fixed, 95% CI) 0.79 [0.63, 0.99]
4.50 Adverse events (measured using rate of falls): gait, balance and function 2   Rate Ratio (IV, Fixed, 95% CI) 0.78 [0.62, 0.99]
4.51 Adverse events (measured using rate of falls): other (additional phone support and coaching) 1   Rate Ratio (IV, Fixed, 95% CI) Totals not selected
4.52 Adverse events (measured as number of people who experienced 1 or more falls) 4   Risk Ratio (IV, Fixed, 95% CI) 1.03 [0.85, 1.25]
4.53 Adverse events (measured using continuous measure of pain) 3 242 Std. Mean Difference (IV, Fixed, 95% CI) ‐0.04 [‐0.29, 0.22]