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. 2022 Sep 3;14:1559–1573. doi: 10.2147/NSS.S356182

Table 4.

Association Between Single Parasomnia Characteristic and Current Wheeze and Ever Asthma

Current Wheeze Ever Asthma
Crude Model Adjusted Model I Adjusted Model II Crude Model Adjusted Model I Adjusted Model II
OR (95% CI) p p* OR (95% CI) p p* OR (95% CI) p p* OR (95% CI) p p* OR (95% CI) p p* OR (95% CI) p p*
Full-term
NREM
 Sleep Walking 0.82 (0.60–1.12) 0.201 0.201 1.21 (0.86–1.71) 0.280 0.327 1.22 (0.86–1.73) 0.268 0.313 0.72 (0.53–0.99) 0.040 0.047 0.99 (0.71–1.39) 0.963 0.963 1.03 (0.73–1.45) 0.873 0.873
 Sleep Terror 1.91 (1.62–2.25) <0.001 <0.001 1.81 (1.50–2.18) <0.001 <0.001 1.76 (1.46–2.14) <0.001 <0.001 1.69 (1.44–1.98) <0.001 <0.001 1.67 (1.40–2.01) <0.001 <0.001 1.66 (1.38–1.99) <0.001 <0.001
REM
 Sleep Talking 1.57 (1.35–1.83) <0.001 <0.001 1.33 (1.11–1.59) 0.002 0.003 1.32 (1.10–1.58) 0.003 0.004 1.36 (1.17–1.59) <0.001 <0.001 1.21 (1.02–1.43) 0.032 0.045 1.20 (1.01–1.43) 0.039 0.055
 Sleep Restless 2.15 (1.91–2.42) <0.001 <0.001 1.80 (1.57–2.06) <0.001 <0.001 1.75 (1.53–2.01) <0.001 <0.001 1.78 (1.58–1.99) <0.001 <0.001 1.54 (1.35–1.75) <0.001 <0.001 1.51 (1.32–1.72) <0.001 <0.001
 Nightmare 1.30 (1.06–1.60) 0.014 0.020 1.47 (1.16–1.87) 0.001 0.002 1.46 (1.15–1.85) 0.002 0.004 1.27 (1.04–1.55) 0.020 0.028 1.44 (1.16–1.80) 0.001 0.002 1.46 (1.17–1.83) 0.001 0.002
Others
 Bruxism 1.71 (1.51–1.94) <0.001 <0.001 1.50 (1.30–1.73) <0.001 <0.001 1.48 (1.28–1.71) <0.001 <0.001 1.52 (1.35–1.72) <0.001 <0.001 1.32 (1.15–1.51) <0.001 <0.001 1.30 (1.14–1.50) <0.001 <0.001
 Enuresis 1.20 (0.97–1.49) 0.092 0.107 1.06 (0.82–1.37) 0.649 0.649 1.08 (0.84–1.40) 0.542 0.542 1.08 (0.87–1.33) 0.492 0.492 1.06 (0.83–1.35) 0.637 0.743 1.10 (0.87–1.41) 0.426 0.497
Preterm, ≤ 36 wk
NREM
 Sleep Walking 1.32 (0.63–2.75) 0.459 0.459 1.84 (0.82–4.14) 0.139 0.139 2.13 (0.91–4.98) 0.081 0.081 1.44 (0.71–2.96) 0.316 0.316 2.21 (1.01–4.88) 0.049 0.049 2.37 (1.06–5.34) 0.037 0.037
 Sleep Terror 2.58 (1.63–4.10) <0.001 <0.001 2.59 (1.52–4.41) <0.001 <0.001 2.91 (1.66–5.11) <0.001 <0.001 2.52 (1.59–4.01) <0.001 <0.001 3.57 (2.11–6.05) <0.001 <0.001 3.74 (2.17–6.46) <0.001 <0.001
REM
 Sleep Talking 2.38 (1.55–3.68) <0.001 <0.001 2.40 (1.47–3.94) 0.001 0.002 2.55 (1.53–4.24) <0.001 <0.001 2.03 (1.30–3.17) 0.002 0.004 1.92 (1.15–3.21) 0.013 0.015 1.94 (1.14–3.28) 0.014 0.020
 Sleep Restless 2.74 (1.92–3.91) <0.001 <0.001 2.59 (1.72–3.90) <0.001 <0.001 2.58 (1.70–3.93) <0.001 <0.001 2.56 (1.79–3.65) <0.001 <0.001 2.44 (1.60–3.70) <0.001 <0.001 2.34 (1.53–3.58) <0.001 0.002
 Nightmare 2.25 (1.29–3.91) 0.004 0.006 2.23 (1.22–4.27) 0.010 0.014 2.39 (1.24–4.59) 0.009 0.013 1.98 (1.12–3.49) 0.019 0.022 2.27 (1.19–4.34) 0.013 0.015 2.24 (1.15–4.37) 0.018 0.021
Others
 Bruxism 2.20 (1.52–3.17) <0.001 <0.001 1.96 (1.29–2.98) 0.002 0.004 2.05 (1.33–3.16) 0.002 0.004 2.12 (1.47–3.07) <0.001 <0.001 2.05 (1.35–3.13) 0.001 0.002 2.12 (1.37–3.27) 0.001 0.002
 Enuresis 1.76 (1.01–3.08) 0.047 0.055 1.96 (1.05–3.68) 0.036 0.042 2.35 (1.21–4.57) 0.012 0.014 1.94 (1.12–3.35) 0.018 0.022 2.30 (1.23–4.29) 0.009 0.015 2.56 (1.34–4.90) 0.005 0.009

Notes: p *p corrected for multiple comparison. Statistically significant results (p < 0.05) are in bold. Model I adjusted for child age, overweight/obesity, gender, mother’s educational level, father’s educational level, family income, family structure, family allergic history, family sleep disorder history; Model II further adjusted for maternal age at delivery, maternal pre-pregnancy overweight, maternal smoking, maternal drinking, negative life event, cesarean delivery, low birthweight, multiple pregnancy, breastfeeding, passive smoking, pet keeping during first year of life.

Abbreviations: REM, rapid eye movement; NREM, non-rapid eye movement; OR, odd ratio; CI, confidence interval; wks, week.