Table 4.
Association Between Single Parasomnia Characteristic and Current Wheeze and Ever Asthma
| Current Wheeze | Ever Asthma | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Crude Model | Adjusted Model I | Adjusted Model II | Crude Model | Adjusted Model I | Adjusted Model II | |||||||||||||
| OR (95% CI) | p | p* | OR (95% CI) | p | p* | OR (95% CI) | p | p* | OR (95% CI) | p | p* | OR (95% CI) | p | p* | OR (95% CI) | p | p* | |
| Full-term | ||||||||||||||||||
| NREM | ||||||||||||||||||
| Sleep Walking | 0.82 (0.60–1.12) | 0.201 | 0.201 | 1.21 (0.86–1.71) | 0.280 | 0.327 | 1.22 (0.86–1.73) | 0.268 | 0.313 | 0.72 (0.53–0.99) | 0.040 | 0.047 | 0.99 (0.71–1.39) | 0.963 | 0.963 | 1.03 (0.73–1.45) | 0.873 | 0.873 |
| Sleep Terror | 1.91 (1.62–2.25) | <0.001 | <0.001 | 1.81 (1.50–2.18) | <0.001 | <0.001 | 1.76 (1.46–2.14) | <0.001 | <0.001 | 1.69 (1.44–1.98) | <0.001 | <0.001 | 1.67 (1.40–2.01) | <0.001 | <0.001 | 1.66 (1.38–1.99) | <0.001 | <0.001 |
| REM | ||||||||||||||||||
| Sleep Talking | 1.57 (1.35–1.83) | <0.001 | <0.001 | 1.33 (1.11–1.59) | 0.002 | 0.003 | 1.32 (1.10–1.58) | 0.003 | 0.004 | 1.36 (1.17–1.59) | <0.001 | <0.001 | 1.21 (1.02–1.43) | 0.032 | 0.045 | 1.20 (1.01–1.43) | 0.039 | 0.055 |
| Sleep Restless | 2.15 (1.91–2.42) | <0.001 | <0.001 | 1.80 (1.57–2.06) | <0.001 | <0.001 | 1.75 (1.53–2.01) | <0.001 | <0.001 | 1.78 (1.58–1.99) | <0.001 | <0.001 | 1.54 (1.35–1.75) | <0.001 | <0.001 | 1.51 (1.32–1.72) | <0.001 | <0.001 |
| Nightmare | 1.30 (1.06–1.60) | 0.014 | 0.020 | 1.47 (1.16–1.87) | 0.001 | 0.002 | 1.46 (1.15–1.85) | 0.002 | 0.004 | 1.27 (1.04–1.55) | 0.020 | 0.028 | 1.44 (1.16–1.80) | 0.001 | 0.002 | 1.46 (1.17–1.83) | 0.001 | 0.002 |
| Others | ||||||||||||||||||
| Bruxism | 1.71 (1.51–1.94) | <0.001 | <0.001 | 1.50 (1.30–1.73) | <0.001 | <0.001 | 1.48 (1.28–1.71) | <0.001 | <0.001 | 1.52 (1.35–1.72) | <0.001 | <0.001 | 1.32 (1.15–1.51) | <0.001 | <0.001 | 1.30 (1.14–1.50) | <0.001 | <0.001 |
| Enuresis | 1.20 (0.97–1.49) | 0.092 | 0.107 | 1.06 (0.82–1.37) | 0.649 | 0.649 | 1.08 (0.84–1.40) | 0.542 | 0.542 | 1.08 (0.87–1.33) | 0.492 | 0.492 | 1.06 (0.83–1.35) | 0.637 | 0.743 | 1.10 (0.87–1.41) | 0.426 | 0.497 |
| Preterm, ≤ 36 wk | ||||||||||||||||||
| NREM | ||||||||||||||||||
| Sleep Walking | 1.32 (0.63–2.75) | 0.459 | 0.459 | 1.84 (0.82–4.14) | 0.139 | 0.139 | 2.13 (0.91–4.98) | 0.081 | 0.081 | 1.44 (0.71–2.96) | 0.316 | 0.316 | 2.21 (1.01–4.88) | 0.049 | 0.049 | 2.37 (1.06–5.34) | 0.037 | 0.037 |
| Sleep Terror | 2.58 (1.63–4.10) | <0.001 | <0.001 | 2.59 (1.52–4.41) | <0.001 | <0.001 | 2.91 (1.66–5.11) | <0.001 | <0.001 | 2.52 (1.59–4.01) | <0.001 | <0.001 | 3.57 (2.11–6.05) | <0.001 | <0.001 | 3.74 (2.17–6.46) | <0.001 | <0.001 |
| REM | ||||||||||||||||||
| Sleep Talking | 2.38 (1.55–3.68) | <0.001 | <0.001 | 2.40 (1.47–3.94) | 0.001 | 0.002 | 2.55 (1.53–4.24) | <0.001 | <0.001 | 2.03 (1.30–3.17) | 0.002 | 0.004 | 1.92 (1.15–3.21) | 0.013 | 0.015 | 1.94 (1.14–3.28) | 0.014 | 0.020 |
| Sleep Restless | 2.74 (1.92–3.91) | <0.001 | <0.001 | 2.59 (1.72–3.90) | <0.001 | <0.001 | 2.58 (1.70–3.93) | <0.001 | <0.001 | 2.56 (1.79–3.65) | <0.001 | <0.001 | 2.44 (1.60–3.70) | <0.001 | <0.001 | 2.34 (1.53–3.58) | <0.001 | 0.002 |
| Nightmare | 2.25 (1.29–3.91) | 0.004 | 0.006 | 2.23 (1.22–4.27) | 0.010 | 0.014 | 2.39 (1.24–4.59) | 0.009 | 0.013 | 1.98 (1.12–3.49) | 0.019 | 0.022 | 2.27 (1.19–4.34) | 0.013 | 0.015 | 2.24 (1.15–4.37) | 0.018 | 0.021 |
| Others | ||||||||||||||||||
| Bruxism | 2.20 (1.52–3.17) | <0.001 | <0.001 | 1.96 (1.29–2.98) | 0.002 | 0.004 | 2.05 (1.33–3.16) | 0.002 | 0.004 | 2.12 (1.47–3.07) | <0.001 | <0.001 | 2.05 (1.35–3.13) | 0.001 | 0.002 | 2.12 (1.37–3.27) | 0.001 | 0.002 |
| Enuresis | 1.76 (1.01–3.08) | 0.047 | 0.055 | 1.96 (1.05–3.68) | 0.036 | 0.042 | 2.35 (1.21–4.57) | 0.012 | 0.014 | 1.94 (1.12–3.35) | 0.018 | 0.022 | 2.30 (1.23–4.29) | 0.009 | 0.015 | 2.56 (1.34–4.90) | 0.005 | 0.009 |
Notes: p *p corrected for multiple comparison. Statistically significant results (p < 0.05) are in bold. Model I adjusted for child age, overweight/obesity, gender, mother’s educational level, father’s educational level, family income, family structure, family allergic history, family sleep disorder history; Model II further adjusted for maternal age at delivery, maternal pre-pregnancy overweight, maternal smoking, maternal drinking, negative life event, cesarean delivery, low birthweight, multiple pregnancy, breastfeeding, passive smoking, pet keeping during first year of life.
Abbreviations: REM, rapid eye movement; NREM, non-rapid eye movement; OR, odd ratio; CI, confidence interval; wks, week.