Skip to main content
. 2022 Sep 7;8(36):eabg3203. doi: 10.1126/sciadv.abg3203

Fig. 6. Human MTGs reverse the hyperaggressive phenotype of Δnvy males.

Fig. 6.

(A) Gene structures of human MTGs with amino acid sequence identities (%) against nvy within each NHR domain. (B) Pan-neuronal expression of human MTG genes by elav-GAL4, verified in fly head extracts by Western blot. (C) Rescue of the ∆nvy phenotype by pan-neuronal expression of human MTGs under the control of UAS. (D) Schematic of the truncated UAS-nvy constructs lacking each NHR domain. (E) Pan-neuronal expression of UAS-nvy lacking the NHR2 domain failed to rescue the ∆nvy phenotype. ***P < 0.001, **P < 0.01, *P < 0.05, and n.s. P ≥ 0.05 [(C and E): Kruskal-Wallis one-way ANOVA and post hoc Mann-Whitney U test with Bonferroni correction].