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Effects of 3-months of YZD treatment on the expression of PI3K/AKT/GSK-3β pathway related proteins in the hippocampi of APP/PS1 mice. (A) Western blot analysis of PI3K, AKT, p-AKT, GSK-3β, p-GSK-3β. (B) Densitometry of PI3K, (C) Densitometry of p-AKT/AKT, (D) Densitometry of p-GSK-3β/GSK-3β. Values show the mean ± SE (n = 3), differences in the level of significance are: *p < 0.05, **p < 0.01, ##p < 0.01.
