TABLE 4.

The enriched KEGG pathway and the related genes.

Pathway	Genes	Fold enrichment	p Value
Alzheimer’s disease	BACE1, GSK3B, APP, MME, IL1B, PSEN2, MAPT, GRIN2B, SNCA	11.52	0.0000
Neuroactive ligand-receptor interaction	GABRA1, CHRM1, GLRB, PTAFR, HTR1A, HTR2A, GRIN2B, LTB4R	6.21	0.0002
PI3K-Akt signaling pathway	ITGB1, IL4, GSK3B, IL6, CHRM1, NOS3, MET, VEGFA	4.98	0.0007
Pathways in cancer	ITGB1, RET, PRKCG, GSK3B, IL6, HIF1A, MET, VEGFA	4.38	0.0015
Proteoglycans in cancer	ITGB1, PRKCG, PLAU, HIF1A, MET, VEGFA	6.45	0.0018
Hematopoietic cell lineage	IL4, IL6, MME, IL1B, ANPEP	12.35	0.0006
HIF-1 signaling pathway	PRKCG, IL6, NOS3, HIF1A, VEGFA	11.20	0.0008
Calcium signaling pathway	PRKCG, CHRM1, NOS3, PTAFR, HTR2A	6.00	0.0081
Focal adhesion	ITGB1, PRKCG, GSK3B, MET, VEGFA	5.22	0.0130
Rap1 signaling pathway	ITGB1, PRKCG, GRIN2B, MET, VEGFA	5.12	0.0139