Table 4.
Available data of weight and length gain from birth to 4 years (variability ± 2 months) in SRS children and SGA subjects.
| 11p15LOM (8pt) | UPD7 (11 pt) | SGA(7pt) | p value 11p15 vs UPD7 | 11p15 vs SGA | UPD7 vs SGA | |
|---|---|---|---|---|---|---|
| BMI SD at 2y | -2.1 ± 1.5 | -3.07 ± 0.93 | -1.17 ± 0.54 | 0.34 | 0.34 | 0.001 |
| Δ BMI SD from 2y to 3y | -1.45 ± 2.7 | 0.53 ± 0.64 | 0.04 | |||
| Δ BMI SD from 2y to 4y | -1.3 ± 3 | 0.7 ± 0.6 | 0.06 | |||
| Weight gain (kg) birth-1 year | 4.1 ± 0.93 | 3.3 ± 0.56 | 0.23 | |||
|
Weight gain (kg)
Birth-4 years |
8.63 ± 1.3 | 8.1 ± 1.44 | 9.6 ± 1.07 | 0.33 | 0.16 | 0.03 |
|
Weight gain (kg)
2-4 years |
2.5 ± 1.6 | 3.1 ± 1.1 | 0.66 | |||
|
Length gain
Birth-1 year |
23 ± 8.2 | 22.1 ± 4.5 | 0.5 | |||
| Height gain birth-4years | 49.5 ± 6.6 | 44.9 ± 4.9 | 47.3 ± 4.2 | 0.07 | 0.34 | 0.37 |
| Height gain (cm) 2-4 years | 16.7 ± 3.6 | 15 ± 3.3 | 0.34 |
BMI, body mass index; w, weeks; y, years; SGA, small for gestational age; SRS, Silver-Russell syndrome; 11p15, 11p15 loss of methylation; UPD7, maternal uniparental disomy of chromosome 7.The bold numbers indicate a statically significant p-value ( p value ≤ 0.05).