TABLE 4.
Protein-miRNA interaction validation.
APOC1 | APOE | HLA-C | HLA-DQA1 | HLA-DRB1 | TOMM40 | NECTIN2 | |
miR-199a-5p | a, b | 0 | 0 | a, b | 0 | a, b, c | a, b |
miR-199b-5p | a, d | 0 | 0 | a, f | 0 | a, b, c | a, b |
miR-423-5p | 0 | 0 | a, b | a, b | 0 | a, b | a, b |
miR-3184-5p | 0 | 0 | a, b | a, b | 0 | a, b | a, b |
miR-124-3p | a, d | 0 | 0 | a, b | 0 | a, e | 0 |
miR-506-3p | a, b | 0 | 0 | a, b | 0 | a, b | 0 |
miR-1321 | a, b | 0 | 0 | 0 | a, b, c | a, b | 0 |
miR-4731-5p | a, b, c | 0 | 0 | 0 | 0 | a, b | a, b |
miR-491-5p | 0 | a, e | a, b, c | 0 | 0 | a, b | 0 |
miR-663a | 0 | a, b, c, e | 0 | 0 | 0 | a, b | a, b |
miR-744-5p | 0 | a, b | 0 | 0 | 0 | a, b | a, b |
miR-665 | 0 | a, b, c | 0 | 0 | 0 | a, b | a, b |
miR-1286 | 0 | a, e | 0 | 0 | a, b | a, e | 0 |
miR-1908-5p | 0 | a, b, c, e | 0 | 0 | 0 | a, b | a, b |
miR-873-5p | 0 | 0 | a, c | 0 | 0 | a, b | a, c |
In this table, all protein-miRNA interactions were validated with other databases. In the table, a: Starbase database, b: miRwalk database, c: TargetScan database, d: miRanda database (accessed from starbase database), e: miRmap database, f: microT database. “0” denotes there is no interaction between intended protein and miRNA. Edges that passed the validation process has been bolded.