FIG 9.

ARIA-E and -H. Patient on anti-amyloid therapy who developed ARIA-E (T2-FLAIR, A–D) and ARIA-H microhemorrhages (T2*-GRE, E–H). On postdosing T2-FLAIR (B), new left parietal T2-FLAIR hyperintense signal involving the cortex and subcortical white matter with associated local mass effect, consisting of sulcal effacement and gyral expansion. Despite suspension of dosing, the extent of T2-FLAIR abnormality and mass effect progressed at the postdosing follow-up No. 1 (1 month). ARIA-E resolved by postdosing follow-up No. 2 (2 months). On postdosing T2*-GRE, 2 new, treatment-emergent microhemorrhages (mild ARIA-H, F, red arrows) that increased in number over postdosing follow-up examinations with severe ARIA-H at postdosing follow-up No. 2 (H, red circle).