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. 2022 Sep;43(9):E19–E35. doi: 10.3174/ajnr.A7586

Table 2:

ARIA severity gradinga

Radiographic Severity
Mild Moderate Severe
ARIA-E(sulcal and/or cortical/subcortical FLAIR hyperintensity) 1 Location < 5 cm 1 Location 5–10 cm OR>1 Location each <10 cm 1 more location > 10 cm
ARIA-H (microhemorrhage) ≤4 5–9 ≥10
ARIA-H (superficial siderosis) 1 Focal area 2 Focal areas >2 Focal areas
a

ARIA is graded on the basis of treatment-emergent events. For ARIA-H, this count includes cumulative new microhemorrhages or regions of siderosis compared with the baseline, pretreatment examination.