Table 3:

Recommended imaging sequences for baseline imaging and ARIA monitoring examinations based on clinical trial experience and current guidelines^a

	Minimal	Recommended	Notes
Field strength	1.5T	3T	Use of a consistent field strength for serial imaging of a given patient is important; imaging may be performed at 1.5T if a patient is not a candidate for imaging at 3T or 3T scanners are not available at a site
ARIA-E detection	2D-FLAIR	2D- or 3D-FLAIR	Either 2D or 3D is acceptable, whichever can be performed with consistent quality and optimal CSF suppression
ARIA-H detection	T2*-GRE	T2*-GRE (±SWI)	Recommendations for enrollment and dose suspension are based on T2*-GRE detection of blood products; SWI may also be performed for confirmation and may be of value to gather data going forward
Infarct assessment	DWI	DWI	DWI required to differentiate ARIA from acute/subsacute infarct and identification of incidental infarcts

^aAdditional optional sequences may be added per individual site preference.