Table 3:
Diagnostic performance of individual MR imaging findings for the diagnosis of meningitisa
| MR Imaging Findings | Sensitivity | Specificity | PPV | NPV | Accuracy |
|---|---|---|---|---|---|
| Leptomeningeal enhancement | 73.3% (62.6%–82.2%) | 78.1% (78.1%–99.9%) | 98.4% (90.2%–99.7%) | 48.9% (40.0%–57.8%) | 78.0% (69.0%–85.4%) |
| Ventriculitis | 13.8% (7.3%–22.9%) | 100% (84.6%–100%) | 100% (100%) | 22.7% (21.2%–24.2%) | 31.2% (22.7%–40.8%) |
| Cerebritis | 28.7% (19.5%–39.4%) | 100% (84.6%–100%) | 100% (100%) | 26.2% (23.7%–28.9%) | 43.1% (33.7%–53.0%) |
| Infarct | 43.7% (33.1%–54.7%) | 100% (84.6%–100%) | 100% (100%) | 31.0% (27.2%–35.1%) | 55.1% (45.2%–64.6%) |
| Extra-axial purulent material | 32.6% (22.8%–43.5%) | 95.7% (78.1%–99.9%) | 96.6% (80.1%–99.5%) | 27.5% (24.2%–31.0%) | 36.3% (36.3%–55.7%) |
| Intraventricular purulent material | 13.8% (7.3%–22.9%) | 100% (84.6%–100%) | 100% (100%) | 22.7% (21.2%–24.2%) | 31.2% (22.7%–40.8%) |
| Abscess/granuloma | 2.3% (0.28%–8.1%) | 100% (84.6%–100%) | 100% (100%) | 20.6% (20.0%–21.1%) | 22.0% (14.7%–31.0%) |
a
Numbers in parentheses are 95% confidence intervals. Data were obtained from brain MRIs within 7 days of presentation.