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. 2022 Sep;43(9):1325–1332. doi: 10.3174/ajnr.A7607

Table 4:

Diagnostic performance of DCE-MR imaging parameters for each tumor comparisona

Parameters Chondrosarcoma vs Chordoma
Chondrosarcoma vs Metastasis
Chordoma vs Metastasis
nADCmean Vp nADCmean Vp Ktrans (minute−1) Vp Ktrans (minute−1)
Cutoff 1.99 0.03 2.09 0.06 0.12 0.09 0.30
Sensitivity 1.0 (0.68–1) 0.93 (0.66–0.99) 0.93 (0.76–0.99) 0.93 (0.78–0.99) 0.93 (0.78–0.99) 0.80 (0.61–0.92) 0.60 (0.41–0.77)
Specificity 0.86 (0.57–0.98) 0.71 (0.42–0.92) 0.87 (0.60–0.98) 0.93 (0.66–0.9) 0.71 (0.42–0.92) 0.93 (0.66–1) 1.0 (0.68–1)
PPV 0.88 (0.62–0.98) 0.77 (0.50–0.93) 0.93 (0.76–0.99) 0.97 (0.82–1) 0.88 (0.71–0.97) 0.96 (0.80–1) 1.0 (0.74–1)
NPV 1.0 (0.64–1) 0.91 (0.59–0.99) 0.87 (0.60–0.98) 0.87 (0.60–0.98) 0.83 (0.52–0.98) 0.68 (0.43–0.87) 0.54 (0.33–0.73)
Accuracy 0.93 (0.78–0.99) 0.82 (0.63–0.94) 0.91 (0.77–0.97) 0.93 (0.81–0.99) 0.86 (0.73–0.95) 0.84 (0.70–0.93) 0.73 (0.57–0.85)
AUC 0.96 (0.90–1) 0.86 (0.72–1) 0.95 (0.88–1) 0.99 (0.96–1) 0.82 (0.67–0.98) 0.92 (0.84– 1) 0.82 (0.70–0.95)

Note:—PPV indicates positive predictive value; NPV, negative predictive value.

a

Numbers in parentheses represent 95% CIs.