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. 2022 Aug 29;43(37):3578–3588. doi: 10.1093/eurheartj/ehac426

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This article has been co-published with permission in The BMJ, the Lancet Digital Health, and the European Heart Journal © the Authors 2022.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. The articles are identical except for minor stylistic and spelling differences in keeping with each journal's style. When citing this article, a citation from any of the journals listed is appropriate.

PMC Copyright notice

Patient and public engagement to improve clinical research. POSITIVE steps leading to co-creation with patients and the public, and better research using big data sources. Content adapted from the Consensus Statement on Public Involvement and Engagement with Data-Intensive Health Research³⁶ as used in the DaRe2THINK trial programme.²⁷ Adapted from Bunting et al.³⁷ PPI=patient and public involvement.