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. 2022 Aug 23;119(2):520–535. doi: 10.1093/cvr/cvac139

Figure 4.

Figure 4

Predicted endothelial—non-endothelial cell interactions in COVID-19 and IPF lungs. A–C, Heatmaps, visualizing the interaction score for the predicted receptor–ligand pairs (P ≤ 0.05) within the (A) vascular compartment itself (EC–EC interactions), (B) between ECs and epithelial cells, or (C) between ECs and stromal cells in control, COVID-19 and IPF lungs. Only interactions enriched or reduced in COVID-19 and/or IPF vs. control lungs are plotted. In bold indicated and boxed interactions are enriched in COVID-19 or COVID-19 and IPF lungs compared with controls.