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. 2022 Sep 8;122(2):121–131. doi: 10.1016/j.jfma.2022.09.004

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© 2022 Formosan Medical Association. Published by Elsevier Taiwan LLC.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 2 — Anti SARS-CoV-2 spike IgG antibody responses (BAU/mL) in the study subjects. (A) Antibody responses in the study subjects from the three groups at the day before and 28 days after vaccination with the third dose of the mRNA vaccine. (B) Comparison of the antibody responses between individuals following a three- and two-dose vaccination schedule. ChAdOx1/mRNA-1273 indicates a heterologous mRNA-1273 vaccine boost after priming with the adenoviral vectored ChAdOx1 vaccine. The number in parenthesis indicates the interval (weeks) between the first and second doses of the respective vaccines. mRNA-1273/mRNA-1273 indicates a homologous mRNA-1273 vaccine regimen. Mann–Whitney U test was performed to compare the antibody responses between the groups. P values have been indicated when a statistical significance was determined. Abbreviations: ELISA S-IgG.