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. 2022 Jul 28;48(6):e12836. doi: 10.1111/nan.12836

FIGURE 3.

FIGURE 3

TDP‐43 immunohistochemistry in the frontal cortex of two C9orf72 mutation carriers (Cases 6 and 7). TDP‐43 immunoreactive intracellular inclusions and neuropil deposits in two fields of the second layer of the frontal cortex (A, B) and of the fifth layer of the frontal cortex (C, D). Neuronal cytoplasmic inclusions (NCIs) and diffuse granular NCIs (dNCIs) are present. The pattern of TDP‐43 inclusions is consistent with Mackenzie Type B classification. Scale = 20 μm; antibody: pS409/410