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. Author manuscript; available in PMC: 2023 Sep 6.
Published in final edited form as: Circulation. 2022 Aug 8;146(10):770–787. doi: 10.1161/CIRCULATIONAHA.121.057620

Table 7.

Examples of differentially spliced exons upon GATA4 knockdown correlated with known functional modules of the encoded protein.

Differentially spliced region upon GATA4-KD Protein Affected domains Impaired function
chr1:237850754-237850804 RYR2 AKAP interaction domain RyR2 Phosphorylation
chr2:40404891-40404995 SLC8A1 Calx-beta domain Regulatory Ca2+ binding
chr7:151329154-151329224 PRKAG2 CBS domain Nucleotide binding
chr10:90770509-90770572 FAS Transmembrane domain Regulation of apoptosis
chr11:65425757-65425970 RELA IPT domain DNA binding