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. 2022 Sep 7;5:923. doi: 10.1038/s42003-022-03897-6

Fig. 6. Differential expression of quorum-sensing regulated genes in S. epidermidis HAF242 co-cultured with C. acnes 30.2.L1 (D-class) and C. acnes DSM1897 (A-class).

Fig. 6

a Colonies of S. epidermidis HAF242 exhibit inhibition zones on a lawn of C. acnes DSM1897 (A-class) but not on a lawn of C. acnes 30.2.L1 (D-class). b Differential gene expression of S. epidermidis HAF242 (SE) grown in the two co-cultures (co-culture with C. acnes 30.2.L1 (D-class) versus co-culture with C. acnes DSM1897 (A-class)) (FDR-adjusted p-value, cut off: p ≤ 0.05 and fold-change >2 or <−2). c Heat map of all differentially expressed genes in S. epidermidis HAF242 when grown in the two co-cultures (first column; genes encoding hypothetical proteins were excluded). Gene expression was also compared between S. epidermidis grown in co-culture (second and third columns) versus S. epidermidis grown in monoculture (“SE control”).