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. 2022 Aug 25;13:944801. doi: 10.3389/fphar.2022.944801

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Copyright © 2022 Xie, Yang, Liang, Zhu, Yuan and Du.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of TFPS on the histomorphological changes in mice with DNFB induced AD-like symptoms. (A) HE stained section of ear tissue (magnification ×300) (B) The measurement of ear skin epidermal thickness in different experimental groups is presented as relative to that of control group, for which the value is set as 100%. (C) HE staining of dorsal skin tissues (magnification ×400) (D) The measurement of dorsal skin epidermal thickness in experimental groups is presented as relative to that of the control group, for which the value is set as 100%. (E) Staining of mast cells in the dorsal skin tissue (magnification ×300) (F) Calculate the number of mast cells at random locations. All values are represented as means ± S.E.M (n = 3). ###p < 0.001, compared with the control group. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, compared with the DNFB group.