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. 2022 Aug 25;13:944801. doi: 10.3389/fphar.2022.944801

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Copyright © 2022 Xie, Yang, Liang, Zhu, Yuan and Du.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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OPLS-DA analysis on experimental groups. (A) OPLS-DA score chart for control and model groups. (B) Statistically verified scatter plot was obtained through 2000X replacement test for control and model groups. (C) OPLS-DA S-plot of metabolic profiling for control and model groups. (D) Volcano chart by the OPLS-DA analysis for control and model groups. (E) OPLS-DA score plot for model and TFPS groups. (F) Statistically verified scatter plot was obtained by 2000X permutation test for model and TFPS groups. (G) OPLS-DA S-plot of metabolic profiling for model and TFPS groups. (H) Volcano plot for model and TFPS groups.