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. 2022 Aug 25;13:951595. doi: 10.3389/fpsyt.2022.951595

FIGURE 2.

FIGURE 2

Effect of repetitive transcranial magnetic stimulation (rTMS) on depression scores measured with 17 items Hamilton depression rating scale (HAMD-17) at baseline and 4-week after bilateral rTMS or sham treatment in patients with major depressive disorder (MDD) combined with psychotropic drugs. (A) Total score of HAMD-17 at baseline and 4 weeks after treatment. (B) Change in a total score of HAMD-17 from baseline to post-intervention at 4 weeks. (C–G) Change in scores of five factors in HAMD-17; HAMD-SLD (C), HAMD-A/S (D), HAMD-W (E), HAMD-CD (F), and HAMD-R (G). (H–J) Change in scores of three items in HAMD-SLD; sleep onset latency (H), middle awakening (I), and early awakening (J). rTMS group significantly different from the sham group was marked by asterisks. ***p < 0.001, compared with the baseline (A); ###p < 0.001, compared with the sham group at 4 weeks after treatment; *p < 0.05, ***p < 0.001, compared with the sham group (B–J). Graphs show mean ± SEM; n = 68.