FIGURE 2.

(A) Experimental plan for diphtheria toxin (DT) administration in CD4-iDTR Cre⁺ and Cre^– mice from 4 to 8 weeks post-MI. DT (400 ng, i.p.) was administered on days 28, 38, and 48 post-MI. (B) Representative flow cytometry plots for circulating CD4⁺ and CD8⁺ T-cells in CD4-iDTR Cre^– and CD4-iDTR Cre⁺ mice at 7 days post-injection (i.p.) of first DT dose (35 days post-MI) (left), and their group quantitation (right). Data is shown from 1-representative experiment. Mean ± SD is shown. Unpaired 2-tailed Student’s t-test was used in (B). *P < 0.05 represents significance with respect to the indicated groups.