Figure 1.

Double plotted representative actograms of male and female C57 and BTBR mice housed in DD. BTBR mice overall had shorter FRPs compared to C57 mice (p < 0.0001). BTBR male mice had significantly shorter FRPs compared to C57 male mice and BTBR female mice. BTBR female mice had significantly shorter FRPs compared to C57 male and female mice. No differences were found between C57 male and female mice. BTBR mice also had shorter alphas compared to C57 mice. BTBR male mice showed shorter alphas compared to C57 male mice and BTBR female mice and BTBR female mice showed shorter alphas compared to C57 male and female mice. BTBR mice also had higher total wheel running activity compared to C57 mice. BTBR male mice had significantly higher total wheel running activity compared to C57 male mice and BTBR female mice had significantly higher total wheel running activity compared to C57 female mice. But no differences were found when comparing BTBR male and female mice or C57 male and female mice. Abbreviations: DD = constant darkness; FRPs = freerunning periods.

*p < 0.05.