Skip to main content
. 2022 Aug 25;14:888784. doi: 10.3389/fnagi.2022.888784

FIGURE 6.

FIGURE 6

Low doses of LEV protect neurons from neuronal loss, whereas high doses of LEV induce the apoptosis of neurons. (A,B) The protein levels of SYP, NeuN, PSD95, Bax, and Bcl2 were determined in the brains of KA (10 mg/kg)- or LEV (50, 100, 150, or 200 mg/kg)+KA-treated APP23/MAPT mice, as determined by western blots. The optical densities of bands in the western blots were evaluated using ImageJ software (*P < 0.05; **P < 0.01; and ***P < 0.001 vs. the control group; #P < 0.05; ##P < 0.01; and ###P < 0.001 vs. the KA-only group). KA, kainic acid; LEV, levetiracetam.