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. 2022 Aug 25;13:907219. doi: 10.3389/fgene.2022.907219

FIGURE 4.

FIGURE 4

Binding site of mir-580 and STAT3 (A); luciferase reporter gene assay verified the targeting relationship between mir-580 and STAT3 (B,C); protein expression level of STAT3 after mir-580 overexpression (D); knockdown of CircPUM1 and STAT3 protein expression in the OSCC cell line (E); expression of STAT3 in OSCC cells after 4 Gy irradiation (F). p < 0.05 (∗), p < 0.01 (∗∗), and p < 0.001 (∗∗∗).