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. 2022 Aug 25;13:949314. doi: 10.3389/fgene.2022.949314

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Copyright © 2022 Cai, Ji, Wu, Chen, Zheng, Chen, Zhang, Xie, Huang, Chen, Lin, Lin, Chen and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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TMB analysis of the prognostic signature. (A,B) The waterfall plots of the tumor mutation rate in the high-risk group (A) and low-risk group (B) based on the prognostic signature. (C) The bean plot for the differences in TMB between high- and low-risk groups. (D) The correlation curve between TMB and the risk score. (E) Kaplan–Meier survival curves of BC patients between the H-TMB and L-TMB groups. (F) Kaplan–Meier survival curves of BC patients across H-TMB + high risk, H-TMB + low risk, L-TMB + high risk, and L-TMB + low risk. TMB, tumor mutational burden; H, high; L, low.