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. 2022 Aug 25;13:949314. doi: 10.3389/fgene.2022.949314

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Copyright © 2022 Cai, Ji, Wu, Chen, Zheng, Chen, Zhang, Xie, Huang, Chen, Lin, Lin, Chen and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Survival, tSNE, and tumor microenvironment analysis of three distinct subgroups of BC divided by consensus clustering. (A) Consensus matrix with optimal k = 3. (B) Kaplan–Meier survival curves of BC patients’ OS among the three different subgroups. (C) Sankey diagram of the relationship between the three different subgroups and risk score. (D) tSNE analysis among the three different subgroups. (E) tSNE analysis between the high-risk and low-risk groups. (F–H) The boxplots for StromalScore (F), ImmuneScore (G), and ESTIMATEScore (H) among the three different subgroups. tSNE, t-Distributed Stochastic Neighbor Embedding; BC, breast cancer; OS, overall survival.