Figure 4.

Constructed ceRNA networks. The left subnetwork consisted of upregulated miRNAs, downregulated mRNAs, and downregulated lncRNA/circRNAs; the right subnetwork consisted of downregulated miRNAs, upregulated mRNAs, and upregulated lncRNA/circRNAs. Green arrow, lncRNA/circRNA; orange circle, mRNA; purple rhombus, miRNAs; combination of brown line and semicircle, inhibition or degradation, respectively; light green line or arrow, promotion. A large or small shape (green arrow/orange circle/purple rhombus) indicates upregulation or downregulation, respectively.